Ethnobotanical and Pharmacological Study of Aspidosperma nitidum Benth (Apocynaceae) – a Review
DOI:
https://doi.org/10.37002/biodiversidadebrasileira.v11i3.1716Palavras-chave:
Pharmacological activity of Aspidosperma nitidum , properties of ApocynaceaeResumo
Carapanaúba (Aspidosperma nitidum) is a tree up to 25 meters high and 40 to 60cm in diameter, straight and with a striated trunk. It is a very resistant and easy to use plant mainly for making cables and tools. In addition to the use of this species in the timber industry, this plant has many medicinal properties. Among the pharmacological properties are antinociceptive, anti-inflammatory, antimicrobial, antioxidant, acetylcholinesterase inhibitory, gastroprotective, antitumor and antimalarial activities. The metabolites responsible for antinociceptive activity were not found in the investigated literature. For anti-inflammatory activity, possible activities of the compounds lupeol, sistoterol and stigmasterol were found. For antimicrobial activity, alkaloids, steroids, triterpenes and pentacyclics may be involved in the process. Alkaloids may be related to antioxidant activity. Regarding the inhibitory activity of acetylcholinesterase, the carbonyl ester may be responsible for such activity. For gastroprotective and antitumor activity, alkaloids were also found in the literature as possible involved in the process. Regarding antimalarial activity, the substances responsible for the mentioned activity were not found. The present work reviewed the ethnobotanical and pharmacological properties of Aspidosperma nitidum.
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