Ethnobotanical, Medical, Therapeutical and Pharmacological Study of Carapa guianensis Aublet – a Review


  • Inês Ribeiro Machado Universidade Estadual do Norte Fluminense Darcy Ribeiro
  • Keila Rêgo Mendes Instituto Chico Mendes



Carapa guianensis, popularly known as andiroba, belongs to the Meliaceae family of plants. The oil extracted from the andiroba seed is thick, dark yellow in color and is used as a raw material for illumination lamps and in the cosmetics industry for the manufacture of lotions, shampoos, creams and soaps. In addition, andiroba also has therapeutic and pharmacological attributes, with genotoxic, anthelmintic, healing, trypanocidal, leishmanicidal, repellent, larvicidal, anti-allergic, anti-inflamatory, acaricidal, antimalarial, antioxidant and antitumor. The present work reviewed the Carapa guianensis medical, therapeutic and pharmacological properties. For genotoxic activity, no toxicity was found for the DNA of the tested animals. The compounds responsible for healing activity in seed oil were taninins, saponins and alkaloids. No compounds responsible for trypanocidal activity were found. The compounds responsible for the leishmanicidal activity were fatty acids and phenolic compounds. No compounds responsible for repellent and larvicidal activity were found. Tetranortriterpenoids was found as responsible for the anti-allergic and anti-inflammatory activity. No compounds responsible for acaricidal activity were found. 6α-acetoxygedunin was the compound responsible for the antimalarial activity. In the antioxidant and antitumor activity from the seed oil were not found compounds involved.


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